EBV-specific adoptive immunotherapy

it feels like most of the time news are centred around discoveries that seem to be focused on the RRMS types… I have just read this article and it seems to shed light also for SPMSers too! :)

Based on the patient’s Epstein Barr Virus (EBV) researchers have managed to ” harvest some of [the patient’s] own T cells and grow them in the lab together with an EBV vaccine. Then, the boosted cells are transferred back to the patient intravenously.”

Of course, as always, further tests are required but the results seem to be promising and the test patient claims to have experienced a change for the better. Read more about the treatment (EBV-specific adoptive immunotherapy) and the test patient’s experience here: http://www.medicalnewstoday.com/articles/272326.php#rate



Smoking & MS

On April 8th, Medical News Today reported (yet again) on a link between smoking & MS.. This new study shows that smoking may increase the risk of multiple sclerosis in people who also have specific established risk factors for MS.


The study also found that among those with high levels of the Epstein-Barr virus antibodies, smokers were twice as likely to have MS as those who had never smoked. The same association was not seen in those with low antibody levels. The risk of MS associated with smoking was not different in people with and without the HLA-DR15 gene.

The study’s author Claire Simon, ScD, with Harvard School of Public Health in Boston said that “the consistency of an association between MS, smoking and the body’s immune response to the Epstein-Barr virus based on these three distinct, geographically diverse studies suggests this finding is not due to chance.” In this way, reasons so as to why some people develop MS and others not may be apparent.

For the whole study, click on the Medical News Today link on the right ; )

MS cause found..?

The possible cause of MS might have been found…but further research needs to be done…

Published 05.11.2007

Epstein-Barr virus (EBV), a ubiquitous B-lymphotropic herpesvirus, has been associated with multiple sclerosis (MS), but direct proof of its involvement in the disease is still missing. MS might result from perturbed EBV infection in the CNS (further research needed to confirm it). However, the research has concluded that EBV persistence and reactivation in the CNS play an important role in MS immunopathology.

Full article can be bought on http://www.jem.org