EBV-specific adoptive immunotherapy

it feels like most of the time news are centred around discoveries that seem to be focused on the RRMS types… I have just read this article and it seems to shed light also for SPMSers too! :)

Based on the patient’s Epstein Barr Virus (EBV) researchers have managed to ” harvest some of [the patient’s] own T cells and grow them in the lab together with an EBV vaccine. Then, the boosted cells are transferred back to the patient intravenously.”

Of course, as always, further tests are required but the results seem to be promising and the test patient claims to have experienced a change for the better. Read more about the treatment (EBV-specific adoptive immunotherapy) and the test patient’s experience here: http://www.medicalnewstoday.com/articles/272326.php#rate

 

A new, and unique, stem cell therapy for MS patients! :)

It is always great news to hear about the use of stem cells as therapies for MS. There seems to be great hope for the future with the use of these and we can only be positive about what is coming :)

I look very much forward to hearing the results of this research and hope we will all be able to benefit from it, soon :)

 

Enjoy the read: http://guardianlv.com/2013/08/unique-stem-cell-therapy-for-ms-patients/

 

Stay well!

/S

another MS breakthrough!

This is great news today :)

As we know, most of the medicine out there nowadays are so-called immunosuppressors – they “knock down” our immune response without selection leaving us highly susceptible to viruses and other infections.

What this new discovery aims at doing is targeting only the autoimmune response to myelin. And how is this done? “…intravenously with an infusion of (the patients. red) own white blood cells, which had been engineered to carry billions of myelin antigens.”

Researchers are hoping that the cells would teach the body to stop attacking myelin. Hope is last to die and remember, it is ‘just’ a breakthrough not a cure.. but we’re getting there!! :)
Read the full article here:

http://www.foxnews.com/health/2013/06/06/medical-breakthrough-for-multiple-sclerosis-sufferers/

/S

And another new MS breakthrough!

Oregon Health & Sciences University (OHSU) were rejoiced by their new discovery which, as they claim, stands a good chance of helping people suffering from MS and a range of other neurological disorders.

The discovery centers around high levels of a particular enzyme not usually found in the brain, but only in those with brain damage due to MS, stroke and conditions.

It is believed if researchers can figure out how to block the enzyme, the brain can repair itself, where insulating shields around nerve cells have been damaged or destroyed (!!!).

“We have a chance now of understanding a whole new process that’s preventing repair of the brain.  And we have the possibility of finding a drug in the next several years that could repair the brain in MS patients and other patients where this nerve sheath is destroyed,” said Sherman (the Lead Researcher).

The next step is to find a drug or combination of medicines that block the enzyme.

Read the whole article here.

MS damage reversed in mice model of MS!!

This is just great news!!!

Science Daily published an article about the research that the Mayo Clinic has been doing with regards to reversing the damage that MS causes to the nerves (both regenerating and repairing them!!) – and the results seem promising!! :) :) :)

http://www.sciencedaily.com/releases/2012/06/120628131414.htm

we’re getting there…. :-)

New MS therapies expected in 2012

Hi all,

I have just come across this interesting video where Dr. Ben Turner quickly highlights the key new MS therapies we can expect in 2012.

Among these you will hear a bit about Fingolimod (Gylenia), Teriflunomide (Aubagio), BG12 (Biogen’s nr. 12 drug) and Alemtuzumab (Lemtrada). He briefly introduces the drugs and gives a short explanation of the known benefits, supported by graphs.

To view the video click here: http://shift.ms/magazine/2012/02/new-therapies-what’s-around-the-corner-in-2012/

Never give up! =)

More genes than previously thought linked to MS!

A new discovery that came from a research aimed at finding out what role genes play in MS has now identified an additional 29 genes adding to a total of 57 genetic clues for MS.

However, it is still emphasized that genes play only a part in MS risk. Other factors, such as vitamin D levels and viral exposure are also believed to play a role. We know that the further somebody is from the equator, the higher his/her risk is (vitamin D from sunlight may be a factor).

The authors explained that T-cells and interleukins appear to play a major role in the development of MS. (…)

Co-author, Alastair Compston, from Cambridge University, said:

“We have implicated genes that are highly relevant to the actions of those drugs. It is now clear that multiple sclerosis is primarily an immunological disease. This is the way to nail this disease and get on top of it.”

(Source: Medical News Today August 10th 2011.)

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