EBV-specific adoptive immunotherapy

it feels like most of the time news are centred around discoveries that seem to be focused on the RRMS types… I have just read this article and it seems to shed light also for SPMSers too! :)

Based on the patient’s Epstein Barr Virus (EBV) researchers have managed to ” harvest some of [the patient’s] own T cells and grow them in the lab together with an EBV vaccine. Then, the boosted cells are transferred back to the patient intravenously.”

Of course, as always, further tests are required but the results seem to be promising and the test patient claims to have experienced a change for the better. Read more about the treatment (EBV-specific adoptive immunotherapy) and the test patient’s experience here: http://www.medicalnewstoday.com/articles/272326.php#rate

 

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A future possibility to predict MS?

Wow… it has really been ages… I really do want to try to keep as updated as I can and follow on news but sometimes work and tiredness gets to you doesn’t it… ? it can be hard to manage :/

I guess it is the thought that counts, and the fact that after all I manage to squeeze in a few lines once in a while… So, today I read something interesting:). One day in the (hopefully near) future they might be able to test for MS long before disease onset.

To find out more about the research conducted on this molecular marker click here.

Enjoy your day!

/S

another MS breakthrough!

This is great news today :)

As we know, most of the medicine out there nowadays are so-called immunosuppressors – they “knock down” our immune response without selection leaving us highly susceptible to viruses and other infections.

What this new discovery aims at doing is targeting only the autoimmune response to myelin. And how is this done? “…intravenously with an infusion of (the patients. red) own white blood cells, which had been engineered to carry billions of myelin antigens.”

Researchers are hoping that the cells would teach the body to stop attacking myelin. Hope is last to die and remember, it is ‘just’ a breakthrough not a cure.. but we’re getting there!! :)
Read the full article here:

http://www.foxnews.com/health/2013/06/06/medical-breakthrough-for-multiple-sclerosis-sufferers/

/S

Promising trials – for MS as well – w. ADULT stem cells use! :)

More good news ahead this sunny day.. :

Using adult stem cells (not embryonic) the researchers have shown both sensation and motor improvements in patients with spinal cord injuries.

Read the whole article here: http://www.mycentraljersey.com/article/20130602/NJNEWS/306020011?odyssey=mod%7Cmostcom

 

Warm regards,

S

Shrinkage of brain region may predict MS

This is an interesting discovery… how the thalamus could become a biomarker for MS because it’s detectable at a very early stage:

http://www.webmd.com/multiple-sclerosis/news/20130423/shrinkage-of-brain-region-may-signal-onset-of-multiple-sclerosis

 

/Sofija

And another new MS breakthrough!

Oregon Health & Sciences University (OHSU) were rejoiced by their new discovery which, as they claim, stands a good chance of helping people suffering from MS and a range of other neurological disorders.

The discovery centers around high levels of a particular enzyme not usually found in the brain, but only in those with brain damage due to MS, stroke and conditions.

It is believed if researchers can figure out how to block the enzyme, the brain can repair itself, where insulating shields around nerve cells have been damaged or destroyed (!!!).

“We have a chance now of understanding a whole new process that’s preventing repair of the brain.  And we have the possibility of finding a drug in the next several years that could repair the brain in MS patients and other patients where this nerve sheath is destroyed,” said Sherman (the Lead Researcher).

The next step is to find a drug or combination of medicines that block the enzyme.

Read the whole article here.

MS Disability linked to sodium buildup in brain

A recent article (Medical News Today) has suggested that a sodium buildup in the brain is related to disability in patients with MS.

The study found that for early-stage MS, specific brain regions were affected. However, for patients witha more advanced MS the accumulation was found throughout the whole brain.

Sodium buildup in motor areas of the brain correlated directly to the degree of disability seen in the advanced-stage patients“.

– a 3T sodium MRI scan can detect the sodium buildup in the brain:

Brain sodium MR imaging can help us to better understand the disease and to monitor the occurrence of neuronal injury in MS patients and possibly in patients with other brain disorders“.

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